Thousands of drugs are available in the market. With so many, it can be a challenge to find the combination that will treat a patient effectively, as not all patients are the same.
A study published in Diabetes Care was designed to study the efficacy of a combination of drugs in the treatment of type 2 diabetes. The study focused a cohort of 231 type 2 diabetes patients. Some were given insulin treatment and others received a combination of exenatide and pioglitazone.
The results were observed after an average of 12 months follow-up. The findings showed that those who received the drug combination had a drastic improvement in hypoglycemia. The effects of the therapy were present independently of ethnicity, BMI or sex. Additionally, subjects treated with insulin experienced significantly greater weight gain than the drug combination group.
The researchers concluded that the combination of exenatide and pioglitazone as a therapy for blood sugar control is a very effective option in patients with poorly controlled type 2 diabetes.
Both drugs are used in diabetes control. Read on to find out more details about them.
The Drugs
Exenatide
This drug is used to treat type 2 diabetes, and is used together with diet and exercise. Exenatide increases the release of insulin from the pancreas and mimics actions of other hormones involved in lowering blood sugar levels.
Pioglitazone
Like exenatide, pioglitazone is a medicine that helps the control of blood sugar levels. Its intended use is for the treatment type 2 diabetes, not type 1.
It’s still early to say that this will be the new standard instead of insulin treatment, but it’s a good start to develop an alternative to injections or any form of insulin dependency.
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